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MDSAlgorithm​

USING THE WEB-APP 

STEP 1

Select the most prominent symptom 

STEP 2

Select the second symptom

For metabolic and autoimmune conditions, you can directly access their differential by selecting their respective icon at this step. Additionally, some disorders are categorized based on age, body part localization, and ocular, auditory, and vestibular symptoms in Step 2.

STEP 3

Differential Diagnosis

Genetic and neurodegenerative disorders are organized into six sub-categories based on anatomical localization (corner most black icons) for easy cataloging and referencing.

  1. Cortical/ Subcortical disorders

  2. Basal ganglia disorders

  3. Cerebellum/ Tract disorders

  4. Spinal cord/Tract disorders

  5. Peripheral nerves disorders

  6. Systemic/ Dysmorphic disorders

 

These are followed by etiology subclass icons and, finally, the differential diagnosis. Salient features are mentioned below each differential, with key distinguishing features emphasized in bold.

ETIOLOGY CLASSES 

  1. CORTICAL/ SUBCORTICAL

    • DEGENERATIVE DEMENTIAS

    • LEUKODYSTROPHY

    • LYSOSOMAL (C) DISORDERS

  2. BASAL GANGLIA

    • MONOGENIC PARKINSON'S DISEASE 

    • ATYPICAL PARKINSONISM

    • PRIMARY DYSTONIA (DYT)

    • DOPAMINE BIOAMINE DEFECTS AND TRANSPORTOPATHIES

    • AMINO-ORGANIC ACIDURIA DISORDERS

    • MINERAL DEPOSITION SYNDROMES

    • VITAMIN RESPONSIVE DISORDERS

    • CARBOHYDRATE METABOLISM DISORDERS

    • NEUROACANTHOCYTOSIS SYNDROMES

    • LYSOSOMAL (BG) DISORDERS

    • PAROXYSMAL DYSTONIA/ CHOREA

  3. CEREBELLUM/ AFFERENTS

    • SPINOCEREBELLAR ATAXIA (SCA)

    • MITOCHONDRIAL DISORDERS

    • FRIEDREICH ATAXIA PHENOTYPE

    • ATAXIA WITH OCULOMOTOR APRAXIA PHENOTYPE

    • LYSOSOMAL (CBL) DISORDERS

    • BILE ACID METABOLISM DISORDERS

    • CARBOHYDRATE METABOLISM DISORDERS

    • PEROXISOMAL DISORDERS

    • EPISODIC ATAXIA

  4. SPINAL CORD/ TRACTS

    • HEREDITARY SPASTIC PARAPARESIS (SPG/ HSP)

    • SPASTIC ATAXIA (SPAX)

  5. PERIPHERAL NERVES

  6. MULTISYSTEMIC/ DYSMORPHIC

  7. METABOLIC/ DRUGS/ INFECTIOUS

  8. AUTOIMMUNE

Video 1: How to use the website

Video 2: How to create a home page icon 

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